Cardarine GW501516 Review

Cardarine is also known as GW-501516 or Endurobol. Although it is classified as a Selective Androgen Receptor Modulator (SARM) – it is actually a PPARδ (Peroxisome Proliferator-Activated Receptor) receptor agonist. Therefore, this is an agonist of the AR. That’s because Cardarine is binding to the PPARδ receptors (or shortly AR receptors). These are a group of nuclear proteins located in muscles and the fatty acids of a person.

Based on this, Ligand Pharmaceuticals and GlaxoSmithKline (GSK) created this compound as a product to help with the treatment of muscle wasting associated with aging, cancers, HIV and AIDS, and others.

However, Cardarine GW 501516 was discovered to be effective at helping individuals to build lean muscle mass and burn body fat. It was discovered to be effective even in those individuals who are not engaged in physical activity. It’s quite obvious that it is highly effective for those who do. Initially, Cardarine was called Endurobol, and athletes were using it with a high success rate, helping them to work out harder and for longer periods.

According to users of GW501516 (Cardarine), this SARM is having a positive effect on the vascular system too. Studies indicate it is helpful to increase skeletal muscle mitochondrial biogenesis. Therefore, the muscles are capable of synthesizing more mitochondria. This is helpful at increasing strength and endurance as well as building more muscles.

Since these discoveries, Cardarine became popular in the fitness world. Many people search to buy Cardarine for sale either for research or fitness purposes.

What is Cardarine?

Cardarine is the trade name of the synthetic molecule called GW-501516. Scientists created this molecule to work as a SARM – Selective Androgen Receptor Modulator.

SARMs are known as newer types of drugs that are capable of mimicking the effects of the testosterone hormone. However, they do not offer the same side effects. That’s because SARMs work “selectively” on specific receptors, unlike testosterone. Testosterone is the androgenic hormone that is best known for its ability to develop male secondary sex characteristics and increase muscular mass.

GW501516 is a highly effective product for physique and performance enhancement needs. A lot of anecdotal experiences, as well as studies, prove it. Cardarine is allowing athletes to boost their endurance, stamina, and energy thanks to increased oxygen that their muscles can use. This makes users stronger with an overall enhanced physical performance. Ultimately, Cardarine allows you to gain lean muscle tissues and burn fat.

It is an excellent fat burner compound. Perfect for those who want to reduce body fat and increase performance capability.

What Does Cardarine Do?

Cardarine is an effective and excellent SARM at improving the physical condition of a person. It helps you look much better with reduced body fat percentage and increased lean muscle tissues.

Wondering “How Does Cardarine Work?”

Well, it binds to some specific androgen receptors (AR) and is activating them (stimulating). This makes those androgen receptors work on the nucleus to modulate the expression of genes. Those genes are responsible for producing energy. Thanks to it, mitochondrial biogenesis is enhanced.

*Mitochondrial biogenesis is the process where there is a formation of new mitochondria.

*Mitochondria is a double-membrane-bound organelle that is working for the production of energy in cells.

*Muscle cells have mitochondria, and the more they have, the more energy your muscle cells produce.

Cardarine Benefits

Provided the information above, it is clear that Cardarine is offering a lot of different benefits. Administering Cardarine (GW-501516) correctly, individuals are likely to get the following benefits:

  • Enhances endurance. In fact, this is the main benefit that people are searching for when using Cardarine. The increased endurance is one of the best things you’ll get from this SARM. Thanks to increased energy and endurance, athletes can work out longer and harder. Needless to mention that this is likely to lead to more and faster results. Plus, it is highly effective when intense physical exercises are involved.
  • Burns fat. Cardarine GW501516 is one of the best SARMs out there for burning body fat. Numerous scientific discoveries, as well as anecdotal experiences from people who already used Endurobol, said that it is a highly effective product at burning fat. Those who want to reduce BF% would really love it.
  • Improves cardiovascular health. This is an amazing compound for cardiovascular health according to users of this SARM. They said that cardiovascular health was improved because it increases the good cholesterol levels (HDL) and reduces the bad type of cholesterol levels (LDL).
  • Reduces inflammation. There were reports indicating that Cardarine seems to be effective at reducing inflammation too. That’s mostly noticed by those people who suffer from inflammation-related health issues such as asthma or arthritis. They said that during the use of GW 501516, the use of NSAIDs can be reduced or stopped altogether.
  • Boosts physical function. Because of all the physical benefits, Cardarine (GW-501516) has to offer, the overall physical functions can be improved too. It is mostly seen by aging individuals. Elderly people can greatly benefit from this SARM too.

Cardarine Results

Pretty much everyone who is using Cardarine SARM is reporting similar effects. According to those experiences, you don’t really feel Cardarine in the very few weeks after you start using it. Nonetheless, by the end of 2-4 weeks of continuous use of Cardarine SARM, you would feel a rush of energy.

According to reports with Cardarine results, the energy levels start to flow in your body more and more. While that’s obviously helpful in the gym, that’s helping people in their everyday life activities too. They report being able to lift heavier weights by that time and increasing the number of reps per cycle.

Needless to mention that your body looks start to change too. In a few weeks, you would start noticing how the fat “melts” off you and the muscles start growing. That’s why the overall Cardarine transformation can be amazing. Both in terms of how your weight lifting abilities can drastically improve, as well as how your body looks with less fat and more lean tissues.

In short, most people are very happy with Cardarine results by the end of the cycle, which is 8 weeks long. In the end, those are some amazing results!

GW501516 - Cardarine Dosage

Most commonly, the Cardarine administration method is in oral form. Either as a liquid or as capsules. Before determining the Cardarine dosage specifically for you, it is important to understand that it can vary depending on your specific goals. Personal response to the drug is another important factor to consider.

Generally, the common dosages of Cardarine are 10-20 mg per day. Nonetheless, there are people who are using as much as 40-50 mg/day. Obviously, such doses are administered only by those who previously used lower doses of GW 501516 and they responded well to it.

The administration period is 6-8 weeks. It is best to start slowly and then gradually increase in order to make sure you don’t get side effects.

Some people administer Cardarine alone with a high success rate. Nonetheless, people with more experience can try it alongside other SARMs. Common stacks are Ostarine (MK-2866), Andarine (S4), Ligandrol (LGD-4033) or Testolone (RAD-140).

  • PS: If you use Cardarine GW-501516, make sure you have enough daily water intake. It reduces side effects risks and maximizes efficacy.

Ostarine and Cardarine Stack

One of the most common SARMs stacks is the Ostarine and Cardarine stack. The results of running these 2 compounds combined are purely amazing. A lot of athletes and bodybuilders use this duo and achieve stunning fat loss benefits. That’s because both Ostarine and Cardarine are considered some of the best weight and fat loss SARMs out there.

That’s why you could lose total body fat of 8-10% during an 8 week cycle! Obviously, with a proper diet and workout. Additionally, MK-2877 and GW-501516 together would make sure you’re going to keep your muscles and strength during this cycle. This is one of the best stacks out there for those looking at weight loss and fat burning SARMs.

Example of Ostarine and Cardarine stack cycle:

  • Week 1-8: Ostarine 15 mg a day and Cardarine 10 mg a day.

Plus, because they do not suppress your testosterone, there’s no need for a Post Cycle Therapy (PCT) plan after this cycle.

Other Cardarine Stacks

Cardarine is a very versatile compound that can be stacked with various different products for achieving great results. It depends on what exactly you’re searching for.

Peptides are often stacked with Cardarine. Which ones greatly depends on your goals. It can be for health purposes, weight loss, cutting, or others.

Additionally, Clenbuterol for enhanced fat loss benefits. Cardarine GW-501516 is a great product to help people lose weight. It burns fat and preserves muscles. So does Clenbuterol but in different ways. When stacking these two, you transform your body into a fat burning machine.

Another example can be Testosterone. Many people, especially beginners, run Testosterone with Cardarine. Testosterone is going to work on a hormonal level while Cardarine is on androgen receptors. Both can help you burn fat, but you’re going to notice enhanced muscle and strength gaining efficiency. Testosterone is great at increasing lean muscle mass and Cardarine boosts it.

When To Take Cardarine?

Cardarine is best taken by people who are having an active lifestyle, those who are dieting and have a lower body fat percentage. Also, it is best taken by those who were already dieting and working out for months before starting with this or any other SARM.

As for when to take it during the day – best to use it at a consistent time on a daily basis. Although half-life is longer, you would get maximum results when used throughout the day. For example, in the morning and evening. You can use it with or without food.

Cardarine Half Life

Cardarine is going to stay in your system for about 2 days or so after you stop its use. GW-501516 half-life is about 12-36 hours. Nevertheless, it can be different depending on various factors. Level of hydration, body fat percentage, lifestyle, and other factors come into play.

How to Increase Cardarine Effectiveness?

A direct impact on the effectiveness of GW501516 is the level of hydration. You need to drink water because a lower concentration of water in the body would reduce Cardarine efficiency. That’s because this substance binds to androgen receptors. Those are receptors within muscle cells that require a lot of water.

GW-501516 Cardarine SARM for Weight Loss

Cardarine can be a powerful, safe, and one of the most important factors – a legal supplement for weight loss purposes. GW501516 is an awesome choice for such needs. This is a synthetic drug that helps preserve muscles while greatly boosting fat loss processes. It would help you lose weight fast and be fairly safe. This compound alone would help a lot, but it would be even more helpful when stacked with other SARMs.

Is Cardarine GW-501516 Legal?

Yes, you can buy Cardarine for sale and stay assured that it is absolutely legal to do so. This is not an anabolic steroid or any other prohibited substance in the United States. You can legally buy Cardarine SARM known as GW-501516 effortlessly.

Cardarine Side Effects

I personally never experienced any side effects from using Cardarine. Not a single time through my multiple cycles with this SARM. Nonetheless, I was using it responsibly. Had my diet and training on point with enough sleep and water intake. Additionally, I understand that I am still a lucky one. Some people do report side effects.

I think that it depends on your genetics, lifestyle, dosage, cycle length, and maybe other factors. As you can notice, you may not experience any side effects. Even if you do, it is not necessary you’ll experience all of them.

In the end, people report that the side effects of Cardarine GW 501516 are relatively mild. Studies suggest that the drug is well tolerated when used at proper doses by most people. Anyway, here are some common examples of Cardarine GW-501516 side effects:


This is perhaps the most commonly reported adverse effect of Cardarine. According to studies, this side effect is more likely to occur in people who use higher doses. Caffeine intake might facilitate the apparition of this issue. So, the lower the dosage, the less likely for you to experience headaches.


This side effect is likely to occur too when using Cardarine. Again, this side effect is mostly reported in higher doses. But it can occur if you use other products that are likely to cause it such as antibiotics or ibuprofen with Cardarine.


This is one fairly common side effect with Cardarine. But that’s because of how it works. It increases blood pressure because of increased metabolism and temperature of the body to help you lose fat. Not everyone experiences high blood pressure, but those who do may put extra strain on their heart. Those with already pre existing cardiovascular conditions (hypertension or whatever other) should talk with a doctor before using Cardarine.

Heart Palpitations

This side effect is mostly reported by people who are not having a healthy and active lifestyle. The side effect is not dangerous, but it can be uncomfortable. It generally goes away after a while of using it. Surely disappears when you discontinue GW-501516 though.

Joint Pains

Some people reported joint pains while adding Cardarine. Not enough water intake can be the reason for this side effect. That’s why I recommend drinking enough water. Additionally, adding joint supplements can be helpful. Plus, in a few days/weeks of continuous use, this side effect can disappear.

Muscle Cramps

Muscle cramps occur if the individual is abusing Cardarine and doesn’t use it responsibly.


  • Cardarine is a banned substance by some sports federations. Before using it, make sure your federation allows it if you’re in a tested sport.
  • Drink enough water during the use of GW-501516 because it would enhance efficiency and reduce side effects.
  • Never abuse it. Don’t use too high doses or longer cycles. Best use it with a great diet and workout protocol.
  • GW501516 is a research chemical. There are countries where you can buy it, but you cannot use it as a supplement.
  • Both men and women can use Cardarine GW-501516. Most people tolerate it very well.

Buy Cardarine For Sale

Cardarine GW-501516 is an awesome supplement that would be amazing for your fat burning journey while allowing you to preserve muscles. Obviously, you need to have your diet on point with a great exercise plan. If Cardarine is added – you’ll get great results with enhanced physical performance, increased stamina, strength, energy, and endurance! You would look much better and get your performance to the next level.

If you want to buy Cardarine – go to the list of top rated sources. doesn’t sell SARMs, we’re just a reviewing website. However, customers may find what they are looking for at the Top Rated Stores of SARMs.

FAQ – Frequently Asked Questions

Is it safe to use Cardarine?

Yes, people without pre-existing health conditions related to heart and blood pressure can safely administer it. Make sure to stick to recommended dosages and guidelines.

What are GW-501516 cycle lengths?

Most commonly – 8 weeks. Although you could still use it for up to 12-16 weeks safely. But obviously, if you stick to that long period, better to use lower doses.

How to prevent Cardarine side effects?

By making sure your diet is on point and you regularly exercise while using Cardarine GW-501516 you may lower the risks. Also, drink enough water and make sure you don’t suffer from heart or blood related issues beforehand.

How long does Cardarine take to work?

Cardarine kicks in the system after about 2 hours. That’s why use it 2 hours before working out. Nonetheless, I recommend using it multiple times a day. You would start noticing the effects in about 2-4 weeks of continuous use.

Can I overdose on GW501516?

Overdose is possible only in case of abuse. Do not exceed recommended dosage and you will be safe.

Cardarine stacks?

You can stack it with multiple other compounds because this is a very versatile drug. Other SARMs like Ostarine are most common. But Testosterone and Clenbuterol are popular stacks too.

Where to buy Cardarine?

There are several online retailers that you can buy Cardarine (GW-501516) from. However, we recommend you research the specific SARM store you plan to buy from. This way, you can be sure you’re getting a quality product for the best prices and the best delivery options. Additionally, I recommend carefully reading the reviews before actually purchasing Cardarine or whatever other SARM. This way, you’ll get a better idea of what other people experienced with the SARMs from that store.

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SARMS A admin Updated November 01, 2022 457 1 0
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